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FETAL GROWTH
Most newborn infants weigh between 2 500g and 4 000g at birth. Infants weighing less than 2 500g are called "low birth weight" (LBW). They may have a low birth weight because they are born preterm, because they have had slow intrauterine growth (fetal growth restraint), or because they have soft tissue wasting (recent fetal starvation).
The pattern of fetal growth is usually assessed at birth by correlating the infant's weight and size with the gestational age. Weight, crown-heel length and head circumference are measured and plotted on a size-for-gestational age standard. The combined Denver standard for males and females of all parities is most widely used (see page ...).
Weight for gestational age is usually used to divide newborn infants into different risk categories. Infants born with a birthweight below the 10th percentile for gestational age are referred to as underweight for gestational age (light for dates or small for gestational age). Similarly infants with a birth weight above the 90th percentile are called overweight for gestational age (heavy for dates or large for gestational age). Infants with birth weights falling between the 10th and 90th percentiles are regarded as being appropriate for gestational age. As weight and gestational age are being measured it is more accurate to refer to overweight, underweight and appropriate weight for gestational age. The newborn infant's length and head circumference can also be plotted on similar standards, and reflect the linear growth and brain growth of the fetus.
Some infants are symetrically underweight and short for their gestational age suggesting a prolonged period of slow intrauterine growth. As they have a length and head circumference below the 10th centile they can be correctly labelled as fetal growth restraint (intrauterine growth retardation). In contrast other infants are wasted with a normal length and head circumference suggesting that their weight has recently fallen due to soft tissue wasting. These wasted infants have suffered recent fetal starvation rather than prolonged slow intrauterine growth.
Assessing the gestational age and weight and the routine plotting of each infant on a weight for gestational age standard, is of great clinical importance as this information can be used to predict the perinatal risk of that particular fetus/infant. Head circumference is also important as it reflects brain size. Length is difficult to measure accurately and is not routinely recorded.
Common problems in Preterm and Underweight for Gestational Age Infants
Preterm
UGA
Birth asphyxia
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Meconium aspiration
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Polycythaemia
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Hypothermia
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Hypoglycaemia
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Hyaline membrane disease
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Apnoea
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Poor feeding
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Patent ductus arteriosus
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Birth trauma
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Periventricular haemorrhage
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Jaundice
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Infection
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Congenital abnormalities
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Retarded postnatal growth
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Retarded postnatal development
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 WEIGHT, LENGTH AND HEAD CIRCUMFERENCE FOR GESTATIONAL AGE STANDARDS.
THE HEALTHY NEONATE AND MINOR DISORDERS
 Weight
A weight loss of up to 10% of birth weight may occur during the first 3 to 5 days of life. Birth weight is usually regained by the seventh day. Subsequent weight gain is usually about 200g a week (25-30 g/day) for the first three months.
 Head and neck
Head circumference - 33 to 37 cm (average 35 cm)
Average increase approximately 7.5 mm/week (1 mm a day)
Shape
caput succedaneum: oedematous thickening of the scalp in the presenting area. It disappears within a day or two
anterior fontanelle: diamond-shaped and variable size, normally slightly concave and may be seen to pulsate
moulding: altered head shape in response to pressure, sometimes with overriding cranial bones
plagiocephaly: "parallelogram skull", with flattening of one side of the occiput and the opposite frontal region and face. Distinguish from unilateral craniosynostosis due to premature fusion of one coronal suture with lack of growth on that side (early surgical correction necessary)
craniotabes (softening of skull bones) is a normal finding in most newborns and many infants up to 3 months.
Neck
the newborn baby generally appears to have a short neck. Midline swellings such as dermoid and thyroglossal cysts are uncommon
sternomastoid "tumour" - a hard lump in the body of the sternomastoid muscle appearing some days after birth. Caused by trauma or avascular necrosis. It may cause torticollis which usually improves with physiotherapy. Uncommon.
Eyes
examination difficult at first because of strong reflex closure. Baby often opens eyes if held erect.

pupil should appear black and not grey.
"red reflex" should be present.
colour of iris indefinite and not predictable.
sclerae often have a blue tinge.
tears rare in first few weeks.
infants are able to see from birth and should follow a red or bright moving object.
subconjunctival haemorrhage: a bright red patch, often adjacent to the cornea has no serious significance and disappears within a few weeks.
abnormally large eye/s may indicate congenital glaucoma (early treatment very important).
Nose and mouth
the newborn infant is an obligatory nose breather. Nasal obstruction, congenital (choanal atresia) or acquired (e.g. nasal secretions), may cause feeding problems or respiratory distress.
sucking blisters: thickened areas on the upper lip, usually in the midline.
epithelial pearls are small whitish areas a few mm across, usually visible in the midline on the hard palate. They are of no significance.
tongue-tie when the frenulum linguae is inserted into or near the tip of the tongue, rarely interferes with sucking or future speech and is usually best left well alone.
Teeth
adventitious teeth may occasionally be present at birth. They are usually loose, do not interfere with sucking, and fall out spontaneously. Rarely, primary teeth may also be present at birth.
 Skin
Vernix caseosa
Protective greasy white substance secreted by fetal sebaceous glands. Not present in preterm infants, and decreases in quantity after term.
Traumatic cyanosis of the face
Due to many small petechial haemorrhages in the skin after congestion of the head with the cord around the neck.
Superficial skin peeling
Common during the first week. It is especially marked in post-term or wasted babies.
Hair
Colour at birth is poor guide to future shade. Lanugo is fine facial and body hair which is a feature of preterm babies.
Milia
White pin-head size spots mainly on and around nose. These are tiny sebaceous retention cysts and last a few weeks.
"Mucus burns"
Red scald-like lesions around the mouth and cheeks due to regurgitated gastric juice (high hydrochloric acid content).
"Mongolian spot"
Flat blue-black areas over sacrum or buttocks, and occasionally on back, shoulders, hands and feet. Disappear by 4 years.
Vascular naevi
Salmon patches: superficial capillary haemangiomata may occur over the upper eyelids and on the nape of the neck (stork-bite). They usually fade by 1 year.
Strawberry naevus: a raised capillary haemangioma with a surface resembling a strawberry. At birth, the strawberry-to-be may show as a white (depigmented) patch of skin. Growth is rapid and it may easily reach 4 cm in diameter. It usually starts to subside by 1 year and most have disappeared by 7 years of age. Surgical removal is rarely necessary.
Port wine mark (naevus flammeus): may cover an extensive area. It persists for life. If situated over the ophthalmic division of the trigeminal nerve it may be associated with a meningeal haemangioma (Sturge-Weber syndrome). Large marks may require laser treatment later.
Erythema toxicum
Very common. Red blotchy rash, associated with central pin-head papules (which may look like pustules but contain eosinophils) occurring between the second and eighth days. Seldom seen in preterm infants.
Fat necrosis
Localized areas of induration on back, thighs, or face (after forceps delivery). It has a dark red appearance and may fluctuate. Resolves spontaneously but needs to be differentiated from skin abscesses.
Sclerema
Very firm rubbery feel to the skin. Associated with severe infection, hypothermia or severe asphyxia.
Wasting
Dry, loose skin hangs in folds due to loss of muscle and subcutaneous fat resulting from recent intrauterine starvation.
 Breasts
Breast enlargement is common in both male and female babies, usually lasting a week or two (but may persist for months). It is due to the effect of oestrogen and progesterone. No treatment is necessary. Handling must be avoided as this may cause true mastitis.
 Gastrointestinal tract
Vomiting
Babies normally swallow a variable quantity of air when feeding and commonly bring up a small amount of milk when winded. Occasional large vomits without cause may occur. Persistent vomiting however, should be assessed carefully and investigated especially if bile is present.
Serious causes
alimentary tract obstruction due to atresia, meconium ileus, volvulus, strangulated hernia, inspissated milk, Hirschsprung's disease and necrotising enterocolitis
marked gastro-oesophageal reflux
infection (including urinary tract)
cerebral pathology (including intracranial bleed or meningitis)
metabolic disorders
Faeces
Meconium is passed within 48 hours of birth in the majority of babies. (When passed in utero it usually indicates fetal distress). Obstruction may rarely be caused by a firm meconium plug, and may be relieved by gently inserting a small glycerine suppository into the anus.
Stools replace meconium on day 3 or 4.
Breast milk stools are usually bright yellow (vary from orange to green), may vary from watery to pasty, and may contain mucus or milk curds. Two to five stools are usually passed each day, but the variation ranges from one stool a week to 12 a day.
Cow's milk (formula) stools are pale yellow, firmer and less frequent (up to 5 a day)
"Starvation stools" which occur in under-fed infants are characteristically small and dark green
Blood in stools is commonly due to swallowed maternal blood (distinguished from fetal blood by Apt test)
 Renal function
newborn infants should pass urine within the first 24 hours
boys should pass urine with a good stream (dribbling suggests posterior urethral valves)
in the first few weeks the infant empties his bladder up to 20 times a day
urates may colour the urine heavily leaving a brick-red stain on the nappy (sometimes mistaken for blood)
the newborn kidney is less able to excrete a solute load and has a reduced concentrating capacity in comparison with the older child
Urine collection: most easily done using a collecting bag, but contamination is a risk. Uncontaminated urine may be obtained by suprapubic bladder puncture.
Genitalia
term male infants usually have testes in the scrotum at birth. The majority of incompletely descended testes come down within the first month
preterm babies tend to have incompletely descended testes and a less well-developed scrotum
fluid hernia (soft swelling of scrotum which transilluminates easily) is common. Most disappear spontaneously within the first year
foreskin is normally adherent to the glans penis and cannot be pulled back without trauma: 90% become fully retractable by the age of 3 years. Pulling back the foreskin in infancy is therefore not advisable and routine circumcision is medically unnecessary
a mucoid vaginal discharge is present in nearly all mature female infants at birth
vaginal bleeding occasionally occurs at the end of the first week (a hormone withdrawl effect of no pathological significance)


The physical examination of the newborn infant should be performed in a fixed order to ensure that nothing is forgotten. First basic measurements are made, then the infant is inspected generally. Thereafter the infant is examined by regions starting at the head and ending at the toes. Finally the neurological status is assessed. The step by step examination given below lists what should be done and gives the normal and abnormal findings.
 MEASUREMENTS
 BIRTHWEIGHT
Normal
2500g or above
Between 10th and 90th centile for gestational age
Abnormal
Low birthweight(below 2500g)
Underweight(below 10th centile)
overweight.(above 90th centile) for gestational age
 HEAD CIRCUMFERENCE
Normal
Between 10th and 90th centile for gestational age.
Abnormal
Small head (below 10th centile) or
Large head (above 90th centile) for gestational age
 CROWN-HEEL LENGTH
Normal
Between 10th and centile for gestational age. Measure accurately with tape or preferably measuring box.
Abnormal
Short (below 10th centile or tall (above 90th centile) for gestational age.
 SKIN TEMPERATURE
Normal
Abdominal wall 36 - 36.5°C (or axilla 36.5 - 37°C)
Abnormal
Hypothermia (below 35°C).
 GENERAL INSPECTION
 GESTATIONAL AGE
Normal
Physical and neurological features of term infant.Term (37-41.9 wks).
Abnormal
Immature features in preterm infant (below 37 weeks).
Postterm infants. (42 weeks and above) have long nails and are often wasted
 WELLBEING
Normal
Active, alert.
Abnormal
Lethargic, appears ill.
 APPEARANCE
Normal
No abnormalities.
Abnormal
Gross abnormalities. Abnormal faeces.
 WASTING COLOUR
Normal
Well nourished. Pink tongue.
Abnormal
Soft tissue wasting. Cyanosis, pallor, jaundice, plethora.
 SKIN
Normal
Smooth or mildly dry. Vernix and lanugo. Stork bite, mongolian spots, milia, erythema toxicum, salmon patches.
Abnormal
Dry, marked peeling.Meconium staining.Petechiae, bruising.Large or many pigmented naevi.Capillary or cavernous haemangioma. Skin infection.
Oedema.
 HEAD
 SHAPE
Normal
Caput, moulding.
Abnormal
Cephalhaematoma,subaponeurotic bleed. Asymmetry, anencephaly,
hydrocephaly, encephalocoele
 FONTANELLA
Normal
Open, soft fontanelle with palpable sutures.
Abnormal
Full or sunken anterior fontanelle. Large or closed fontanelles. Wide or fused
sutures.
 HAIR
Normal
Wide familial variation.
Abnormal
Low posterior hair line.
 EYES
 POSITION
Abnormal
Hypertelorism or hypotelorism.
 SIZE
Abnormal
Microphthalmia or macrocornea (glaucoma).
 LIDS
Normal
Mild oedema common.
Abnormal
Marked oedema, ptosis bruising. Narrow palpebral fissures in FAS.
 CONJUNCTIVAE
Normal
May have small subconjunctival haemorrhages
Abnormal
Pale or plethoric.Conjunctivitis.
Excessive tearing when nasolacrimal duct obstructed.
 CORNEA, IRIS AND LENS
Normal
Cornea clear, regular pupil, red reflex.
Abnormal
Opaque cornea,irregular pupil,cataracts, no red reflex, squint, abnormal eye
movements.
 NOSE
 SHAPE
Normal
Small with upturned nostrils.
Abnormal
Flattened in oligohydramnios.
 NOSTRILS
Normal
Both patent. Easy passage of feeding catheter
Abnormal
Choanal atresia. Blocked with dry secretions
 DISCHARGED
Abnormal
Mucoid, purulent or bloody secretions
 MOUTH
 LIPS
Normal
Sucking blisters.
Abnormal
Cleft lip. Long smooth upper lip, no philtrum and thin vermillion border in FAS.
 PALATE
Normal
Epstein's pearls
Abnormal
High arched or cleft palate.
 TONGUE
Normal
Pink
Abnormal
Cyanosed, pale, macroglossia. Posteriorly placed (Pierre-Robin anomaly).
 TEETH
Normal
None at birth
Abnormal
Adventitious or primary teeth.
 GUMS
Normal
Small cysts.
Abnormal
Epulis.
 MUCOUS MEMBRANES
Normal
Pink, shiny.
Abnormal
Thrush, ulcers.
 SALVIA
Abnormal
Excessive if poor swallowing or oesophageal atresia.
 JAW
Normal
Smaller than older child
Abnormal
Micrognathia in Pierre-Robin anomaly.
 EARS
 SITE
Normal
Pinna vertical at term.
Abnormal
Ears rotated backwards with poorly formed upper pinna (low set).
 APPEARANCE
Normal
Familial variation.
Abnormal
Pre-auricular skin tag or sinus. Malformed ears. Hairy ears in I.D.M.
 NECK
 SHAPE
Normal
Usually short.
Abnormal
Webbing, torticollis.
 MASSES
Normal
No palpable lymph nodes or thyroid
Abnormal
Cystic hygroma. Goitre. Sternomastoid tumour.
 CLAVICLE
Abnormal
Swelling or crepitus if fractured.
 BREASTS
Normal
Palpable breast nodules at term 0.5 to 1 cm. Enlarged, lactating breasts
Abnormal
Accessory or wide spaced nipples. Mastitis.
 HEART
 PULSES
Normal
Brachial and femoral pulses easily palpable. 120 - 160 beats per minute.
Abnormal
Pulses weak, collapsing, absent, fast or slow.
 CAPILLARY FILLING TIME
Normal
Less than 4 seconds over chest and peripheries.
Abnormal
Prolonged filling time if infant cold or shocked.
 BLOOD PRESSURE
Normal
Systolic 50 to 90mm at term.
Abnormal
Hypertensive or hypotensive.
 PRECORDIUM
Normal
Mild pulsation felt over heart and epigastrium
Abnormal
Hyperactive precordium.
 APEX BEAT
Normal
Heard maximally to left of sternum
Abnormal
Heard best in right chest in dextrocarida.
 SOUNDS
Normal
Loud, single 2nd heart sound on day 1
Abnormal
Gallop, widely split second sound.
 MURMURS
Normal
Soft, short systolic murmur common on day 1.
Abnormal
Systolic or diastolic murmurs.
 HEART FAILURE
Abnormal
Oedema, hepatomegaly, tachypnoea or excessive weight gain.
 LUNGS
 RESPIRATION RATE
Normal
40-60 breaths per minute. Irregular in REM sleep. Periodic breathing with no change in heart rate or colour.
Abnormal
Tachypnoea - above 60 breaths per minute. Gasping. Apnoea with drop in heart rate, pallor or cyanosis
 CHEST SHAPE
Normal
Symmetrical.
Abnormal
Hyperinflated or hypoplastic chest.
 CHEST MOVEMENT
Normal
Symmetrical.
Abnormal
Asymmetrical in pneumothorax and diaphragmatic hernis.
 RECESSION
Normal
Mild recession in prems
Abnormal
Subcostal recession in respiratory distress.
 GRUNTING
Abnormal
Expiratory grunt in respiratory distress.
 STRIDOR
Abnormal
Inspiratory stridor a sign of upper airway obstruction.
 PERCUSSION
Normal
Resonant bilaterally.
Abnormal
Dull with effusion or haemothorax.
 AIR ENTRY
Normal
Egual air entry over both lungs. Bronchovesicular.
Abnormal
Unegual or decreased.
 ADVENTITIOUS SOUNDS
Normal
Transmitted sounds.
Abnormal
Crackles, wheeze or decreased.
 ABDOMEN
 UMBILICUS
Normal
2 arteries and 1 vein.
Abnormal
1 artery, 1 vein .Infection. Bleeding or discharge. Hernia. Exomphalos.
 SKIN
Abnormal
Periumbilical erythema or oedema.
 SHAPE
Abnormal
Distended or hollow.
 LIVER
Normal
Palpable 1 cm below costal margin, soft.
Abnormal
Enlarged, firm, tender.
 SPLEEN
Normal
Not easily palpated.
Abnormal
Enlarged, firm.
 KIDNEYS
Normal
Often palpable but normal size.
Abnormal
Enlarged, firm.
 MASSES
Normal
No other masses palpable. Full bladder can be percussed.
Abnormal
Palpable mass.
 BOWEL SOUNDS
Normal
Heard immediately on auscultation.
Abnormal
Depressed or absent.
 ANUS
Normal
Patent. Skin tags.
Abnormal
Absent or covered. Displaced anteriorly.
 STOOLS
Normal
Meconium passed within 48 hours of birth. Yellow stools by day 5. Breastfed stool may be green and mucoid.
Abnormal
Blood in or on stool. White stools in obstructive jaundice. Offensive watery stools.
 SPINE
Normal
Coccygeal dimple or sinus. Straight spine.
Abnormal
Sacral dimple or sinus. Scoliosis. Meningomyelocoele.
 GENITALIA
 PENIS
Normal
Urethral opeining at centre of glans.
Abnormal
Hypospadias. Micropenis.
 TESTES
Normal
Descended by 37 weeks
Abnormal
Undescended.
 SCROTUM
Normal
Well formed at term.
Abnormal
Inguinal hernia. Fluid hernia.
 VULVA
Normal
Skin tags, mucoid or bloody discharge.
Abnormal
Fusion of labia.
 CLITORIS
Normal
Uncovered in preterm or wasted infants.
Abnormal
Enlarged in adrenal hyperplasia.
 URINE
Normal
Passed in first 12 hours.
Abnormal
Poor stream suggests posterior urethral valve.
 ARMS
Normal
Flexed position in term infant.
Abnormal
Erb's palsy.
 HANDS
Abnormal
Extra, fused or missing digits. Skin stags. Single palmar crease. Hypoplastic nails
 HIPS
Normal
Click common. Fully abducted.
Abnormal
Dislocated or dislacatable. Limited abduction.
 LEGS
Normal
Mild bowing of lower legs common
Abnormal
Dislocatable. Knees in breech.
 FEET
Normal
Positional deformation.
Abnormal
Clubbed feet. Abnormal toes.
 NEUROLOGICAL STATUS
 BEHAVIOUR
Normal
Alert, responsive.
Abnormal
Drowsy, irritable, jittery.
 POSTION
Normal
Flexion of all limbs at term.
Abnormal
Extended limbs or frog position in preterm and ill infants.
 MOVEMENT
Normal
Active. Moves all limbs equally when awake. Stretches, yawns and twists trunk.
Abnormal
Absent, decreased or asymmetrical movement. Jittery or convulsions
 TONE
Normal
Hypotonia in preterm infants.
Abnormal
Hypotonia or hypertonia. Asymmetrical tone.
 HANDS
Normal
Intermittantly clenched.
Abnormal
Permanently clenched.
 CRY
Normal
Good cry when awake
Abnormal
Weak, high pitch or hoarse cry.
 VISION
Normal
Follow a face, bright light or red object.
Abnormal
Absent or poor following.
 HEARING
Normal
Responds to loud noise.
Abnormal
No response.
 SUCKING
Normal
Good suck and rooting reflexes after 36 weeks gestation.
Abnormal
Weak suck at term.
 MORO REFLEX
Normal
Full extension then flexion of arms and hands. Symmetrical.
Abnormal
Absent, incomplete or asymmetrical response.
When the history has been taken and the physical examination completed, an overall assessment of the infant must be made and a list of the problems compiled. The management of each problem in turn must now be addressed.
 Examination of the Hips:
The hips must be examined in all newborn infants to exclude congenital dislocation or an unstable hip.
The infant is examined lying on his back with the hips flexed to a right angle and knees flexed.
 Ortolani test : Both thighs are held so that the examiner's fingers are over the greater trochanters and his thumbs rest on the inner aspects of each thigh. The thighs are then abducted: if a hip is dislocated, a 'clunk' can be felt and heard as the femoral head slips forward into its normal position in the acetabulum.
 Barlows Test : demonstrates an unstable or dislocatable hip. One hand immobilizes the pelvis (thumb over pubic ramus, fingers over sacrum) while the other hand moves the opposite thigh into mid-abduction. If the hip is unstable, backward pressure on the lesser trochanter with the thumb on the inner side of the thigh causes the femoral head to slip out of the acetabulum. Conversely forward pressure on the greater trochanter with the fingers would tend to cause the head to spring back into the acetabulum. The same procedure is then carried out for the opposite side.